Elizabeth I Buchbinder Selected Research

MEDI3617

11/2021

Combining CTLA-4 and angiopoietin-2 blockade in patients with advanced melanoma: a phase I trial.

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Elizabeth I Buchbinder Research Topics

Disease

49	Melanoma (Melanoma, Malignant) 04/2024 - 06/2014
31	Neoplasms (Cancer) 01/2024 - 01/2015
7	Colitis 01/2024 - 04/2015
5	Neoplasm Metastasis (Metastasis) 01/2024 - 01/2016
4	Brain Neoplasms (Brain Tumor) 10/2023 - 01/2016
3	Rheumatoid Arthritis 12/2023 - 02/2016
3	Disease Progression 03/2023 - 01/2016
2	Uveal melanoma 04/2024 - 10/2023
2	Diarrhea 01/2023 - 01/2023
2	Necrosis 01/2023 - 01/2020
2	Inflammation (Inflammations) 01/2023 - 01/2019
2	Enterocolitis 01/2023 - 01/2020
2	Dermatitis 08/2021 - 04/2015
2	Pneumonia (Pneumonitis) 08/2021 - 01/2019
1	Anemia 04/2024
1	Exanthema (Rash) 04/2024
1	Hyponatremia 04/2024
1	Pruritus (Itching) 04/2024
1	Crohn Disease (Crohn's Disease) 01/2024
1	Acquired Immunodeficiency Syndrome (AIDS) 01/2024
1	Gastritis 01/2023
1	Fibrosis (Cirrhosis) 01/2023
1	Enteritis 01/2023
1	Abdominal Pain (Pain, Abdominal) 01/2023
1	Colorectal Neoplasms (Colorectal Cancer) 01/2023
1	Chronic Disease (Chronic Diseases) 01/2023
1	Lung Neoplasms (Lung Cancer) 01/2022
1	Graft vs Host Disease (Graft-Versus-Host Disease) 01/2020
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2020
1	Microscopic Colitis 01/2020
1	Ulcerative Colitis 01/2020
1	Overweight 01/2019
1	Renal Cell Carcinoma (Grawitz Tumor) 01/2019

Drug/Important Bio-Agent (IBA)

31	Immune Checkpoint InhibitorsIBA 03/2024 - 01/2015
12	IpilimumabIBA 01/2024 - 01/2016
8	pembrolizumabIBA 01/2024 - 02/2016
6	NivolumabIBA 01/2023 - 02/2016
5	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 06/2023 - 01/2016
4	Interleukin-2 (IL2)IBA 03/2024 - 06/2014
4	dabrafenibIBA 06/2023 - 01/2016
4	trametinibIBA 06/2023 - 01/2016
3	SteroidsIBA 01/2023 - 01/2019
3	Proteins (Proteins, Gene)FDA Link 11/2021 - 11/2016
3	VaccinesIBA 01/2021 - 01/2017
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2024 - 01/2015
2	Immunologic Factors (Immunomodulators)IBA 12/2023 - 01/2023
2	Programmed Cell Death 1 ReceptorIBA 10/2023 - 01/2021
2	Biomarkers (Surrogate Marker)IBA 10/2023 - 01/2016
2	Monoclonal AntibodiesIBA 01/2023 - 11/2021
2	InterferonsIBA 01/2023 - 06/2014
2	LigandsIBA 12/2021 - 01/2020
2	CytokinesIBA 08/2021 - 06/2014
2	Adrenal Cortex Hormones (Corticosteroids)IBA 08/2021 - 01/2020
2	CTLA-4 AntigenIBA 01/2020 - 01/2020
1	ulixertinibIBA 04/2024
1	Amylases FDA Link 04/2024
1	ChromatinIBA 04/2024
1	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 01/2024
1	sargramostim (Leukine)FDA Link 01/2024
1	afliberceptIBA 01/2024
1	Messenger RNA (mRNA)IBA 01/2024
1	B7-H1 AntigenIBA 10/2023
1	HLA-A Antigens (HLA-A)IBA 10/2023
1	ErbB Receptors (EGF Receptor)IBA 01/2023
1	LY3022855IBA 01/2023
1	cobimetinibIBA 01/2023
1	VemurafenibIBA 01/2023
1	(2,4- dihydroxy- 5- isopropylphenyl)- (5- (4- methylpiperazin- 1- ylmethyl)- 1,3- dihydroisoindol- 2- yl)methanoneIBA 01/2023
1	Phenobarbital (Luminal)FDA Link 01/2023
1	GlucocorticoidsIBA 01/2023
1	Imiquimod (Aldara)FDA LinkGeneric 09/2022
1	tremelimumabIBA 11/2021
1	MEDI3617IBA 11/2021
1	Angiopoietin-2IBA 11/2021
1	Immunoglobulin G (IgG)IBA 11/2021
1	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 10/2021
1	Interleukin-17 (Interleukin 17)IBA 08/2021
1	CD40 Ligand (CD40L)IBA 08/2021
1	EpitopesIBA 01/2021
1	Protein Subunit VaccinesIBA 01/2021
1	talimogene laherparepvecIBA 06/2020
1	Bevacizumab (Avastin)FDA Link 01/2020
1	Double-Stranded RNA (RNA, Double Stranded)IBA 01/2020
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2020
1	Vitamin D FDA LinkGeneric 01/2020
1	IntegrinsIBA 01/2020
1	A 19IBA 01/2019
1	T-Cell Antigen Receptors (T-Cell Receptor)IBA 01/2019
1	CreatinineIBA 01/2019

Therapy/Procedure

43	Therapeutics 04/2024 - 06/2014
16	Immunotherapy 04/2024 - 01/2015
4	Aftercare (After-Treatment) 01/2023 - 01/2016
3	Drug Therapy (Chemotherapy) 10/2023 - 10/2020
1	Combination Drug Therapy (Combination Chemotherapy) 03/2024
1	Injections 10/2023
1	Oncolytic Virotherapy 10/2023
1	Neoadjuvant Therapy 03/2023
1	Cryotherapy (Therapy, Cold) 09/2022
1	Radiotherapy 01/2020
1	Colectomy 01/2020